"John Dunn (...) created a software that converts protein sequences into music based on the characteristics and frequency of each amino acid. The 20 amino acids were grouped according to acidity, basicity, and polarity. A frequency analysis was conducted on the amino acids to find the most abundant amino acid within each group. The most common amino acid within a group would be assigned the middle C and then the second most common amino acid would be assigned the next note on the keyboard, D, and so forth. Each amino acid within a chemical group will have a unique note, but across groups, there may be overlap of common notes for two different amino acids from distinct groups.
Other aspects of the music, such as instrumentation, would be left to the discretion of the composer. Each of the groups is assigned an instrument and the importance of the each instrument can be controlled by the volume. The genes can be read sequentially or they can also be read randomly. The overall intention of such creative contributions is to mimick the biological process of transcribing the DNA sequences into proteins. Furthermore, Dunn and Bridges added their own creative component by adjusting the instrumentation and tempo to match the biological characteristics of the protein such as starfish being "relatively simple and quite mechanical". Dunn continued from 1992 through 1995 to convert DNA sequences from organisms such as starfish, slime mould, sea urchins, etc. using his algorithm."
Life Music: Improvisation on Genetic Themes
MA Clark and John Dunn